PSA Screening Guidelines and Recommendations
The organizations below provide prostate cancer screening guidelines and recommendations used by doctors and patients, and by PHENpsa.com on the ages to begin and stop PSA screening. Since African American men are at the highest risk for being diagnosed with prostate cancer and dying from the disease, PHENpsa.com adheres to the most aggressive guidelines and recommendations.
Organization
Age to Begin Screening
Age to Stop Screening
Screening Frequency
Organization
American Cancer Society
Age to Begin Screening
Age 50 for men at average risk for prostate cancer and life expectancy of 10 plus years.
Age 45 for men at high risk of developing prostate cancer. This includes African American men.
Age 40 for men at even higher risk (those with more than one first-degree relative who had prostate cancer at an early age).
Age to Stop Screening
70 years or older or less than a 10-year life expectancy
Screening Frequency
Every 2 years
Organization
American Urological Association
Age to Begin Screening
Age 55 at average risk shared decision-making recommended
Age 40 at high risk. African American men should speak with doctor about screening.
Age to Stop Screening
70 years or older or less than a 10-year life expectancy
Screening Frequency
Every 2 years
AA men may require earlier or more frequent screenings
Organization
National Comprehensive Cancer Network
Age to Begin Screening
Age 45 for men who are at average risk
Age 40 for those with:
• African ancestry
• Germline mutation
Age to Stop Screening
Greater than 70 years of age with PSA less than 1.0 ng/mL
Greater than 75 years of age with a PSA less than 3.0 ng/mL have a very low risk of prostate cancer metastases or death and may be counseled to consider stopping PSA testing
Screening Interval
Every year
Organization
US Preventive Services Task Force
Age to Begin Screening
Age 55 for men in the general population
Age less than 55 for men at increased risk. African American men are at increased risk of developing and dying of prostate cancer.
Age to Stop Screening
70 years or older or less than a 10-year life expectancy
Screening Interval
Every 2 years
More research needed for AA and other high-risk men
IMPORTANT:
This information is provided for educational purposes only to support patients in understanding and discussing early detection screening with their doctor. However, this information should not be considered as patient screening guidelines or recommendations, but as educational materials only. Patients should discuss early detection screening with their doctors to understand the risks and benefits, and decisions should only be made between the patient and his doctor.